wreck can. It’s venv aware. Takes full advantage of hierarchical requirement files. Is intuitive. The learning curve is minimal. Written in Python.

[[tool.wreck.venvs]]
venv_base_path = '.venv'
reqs = [
    'requirements/pip',
    'requirements/pip-tools',
    'requirements/prod',
    'requirements/dev',
    'requirements/manage',
    'requirements/kit',
    'requirements/mypy',
    'requirements/tox',
]
[[tool.wreck.venvs]]
venv_base_path = '.doc/.venv'
reqs = [
    'docs/requirements',
    'docs/pip-tools',
]

[tool.setuptools.dynamic]
dependencies = { file = ['requirements/prod.unlock'] }
optional-dependencies.pip = { file = ['requirements/pip.lock'] }
optional-dependencies.pip_tools = { file = ['requirements/pip-tools.lock'] }
optional-dependencies.dev = { file = ['requirements/dev.lock'] }
optional-dependencies.manage = { file = ['requirements/manage.lock'] }
optional-dependencies.docs = { file = ['docs/requirements.lock'] }

reqs fix --venv-relpath='.venv'

reqs fix --venv-relpath='.doc/.venv'

From *.in requirements files would produce *.unlock and *.lock files for venv .venv. Package versions are sync’ed within all requirements files within that venv.