“No, I haven’t sat down to play the games,” said Walton Goggins, who plays pre-war movie star Cooper Howard and his post-war counterpart The Ghoul. “And I won’t. I won’t. I won’t play the games. I’m not interested.”
The reason is actually pretty simple: Goggins doesn’t want to think of the world or the characters of Fallout as elements of a game.
“All of a sudden, I’m looking at this world from a very different perspective, and as something on a screen in which I am an avatar in. I don’t believe that I’m an avatar. I believe The Ghoul exists in the world. I believe that Cooper Howard exists in the world.” he said.
“The best way that I can serve this world and serve the fans of this game, I think, is to go to work every single day and believe the circumstances that I’m presented with,” Goggins said.


Yeah, that’s why they fit more in 76. They were created by pre-War experimentation inspired by real life government experiments and are localized to one area.
It’s not watertight but again, it is probably their best excuse of the 3 they’ve given.
While I largely agree with you, I thought you said the lore is inconsistent so it doesn’t matter?
EDIT: Oh, wait. I kinda see what you’re saying now. My point is that the all the Super Mutants are, gameplay-wise, are big, tough guys. You can write a big, tough enemy class into your game a million different ways, which they did more creatively in Point Lookout. It wasn’t a choice between inconsistent lore and fun, they’re just lazy.