A campaign is under way to drive the UN relief agency for Palestinians, Unrwa, out of existence, its commissioner general has said, days after 18 people were killed when Israeli jets bombed an Unrwa school in Gaza.

Philippe Lazzarini said in an interview that the Israeli government was seeking to close down the agency, having failed to persuade western donors to stop funding it on the grounds of allegations about links between Unrwa staff and Hamas.

“This deliberate attempt to eliminate Unrwa and prevent it from operating would have devastating consequences for the multilateral system, the UN and the cause of a Palestinian transition to self-determination,” Lazzarini said.

He said: “There is a deliberate attempt to eliminate and dismantle the agency and the reason behind that has nothing to do with neutrality issues, but there is a political purpose behind it. Ultimately there is a desire to strip the Palestinians of refugee status and beyond that to undermine the future Palestinian aspiration for self-determination. That is why Unrwa has become such a target.