When installing from Github you only trust the developer and their signed certificate key.
When installing from F-Droid you additionally also have to trust the F-Droid developer’s signature.
Besides that F-droid has its own problems:
https://privsec.dev/posts/android/f-droid-security-issues/
I don’t use F-Droid. I use Obtainium and additionally check signatures in AppVerifier.
In that case, it seems to me that the only threat is the mindless copying of public keys to other servers, as described in the article. But who does so? Do admins not create separate private-public keys for each server?
Thank you for the explanation!