hmmm. To be honest, that’s an okay summary out of context, but it really fails to grasp the essence of the paper. It’s not wrong per say, but it adds irrelevant details while withholding key information. I wouldn’t rely on chatgpt’s summary for this.

There’s a feature of some Long COVID cases (~50%) which is also the defining feature of an illness called ME/CFS which has been caused by various forms of viral infections throughout history. (It is thought that a lot of Long COVID cases are ME/CFS). Anyways this feature is, Post-Exertional Malaise, a worsening of the illness after exertion beyond a certain threshold, which can entail hundreds of symptoms and be permanent.

This paper is a review of some of the biomedical studies looking at what could possibly cause this, and finds there is repeated data of Microvascular (blood vessels) and immunometabolic (metabolic markers relating to immune function) differences with healthy controls.

The leading hypotheses are that this is caused by mitochondrial dysfunction which is mediated by a dysregulated immune system.

Some of my colleagues were co-authors on this paper. I’ll forward the feedback that it is jargony.

What kind of stuff would you encourage posting?

Interesting studies, relevant resources? Or would you prefer discussion type posts?

Or all of the above?

Cool yeah!

I’m really passionate about my field. And a lot of medical professionals have prejudice or believe outdates stereotypes about it. So I’d love to make some posts about it if that’s okay?

Hey I have a MD with residency in Neurology. Then I did a PhD in Neuroimmunology with board certification.

I’m currently doing a hectic mix of teaching two med courses, working on Long COVID research (biomarkers), and working in an understaffed long COVID (now post-viral disease) clinic.

Nice to meet you.

I mostly lurk on lemmy, but that’s because I haven’t found a place I’d like to consistently contribute yet. Maybe here?

Are octopus related to octopus? I mean technically they’re 100% related, but also they aren’t related as related implies not being. Depends on your interpretation.

If you’re healthy.

Sucks to be disabled or immunocompromised or at risk in any other way…

Also, it’s still killing at much higher rates than the flu.

And I won’t even start getting into Long COVID, which I’m currently researching. But it is a major crisis. 2-4 million people unable to work in the US because of it.