cross-posted from: https://piefed.world/c/depression_now/p/933723/does-anybody-else-s-anti-depressants-wear-off-after-taking-a-nap-or-otherwise-sleeping

Duloxetine works great for me until I sleep, then I wake back up into the pit of despair and I feel like I’m supposed to wait until ~24 hours since I last took it in order to take it again. I can’t find any cases of other people reporting this and it’s not something my medical professionals have heard of. It makes it hard if I don’t have energy due to not getting enough sleep the night before so I take a nap, and then when I wake up I still don’t have energy due to lack of willpower. I’ve also found it harder to get out of bed in the morning shortly before taking the medicine.

  • SavvyWolf@pawb.socialEnglish
    2·
    3 months ago

    I actually take my antidepressants right before I go to bed, and they seem to last the next day.

    I do get really upsetti if I stay up later than usual, and am generally lower in mood at night. But that could be a number of things.

    • dingus@lemmy.worldEnglish
      1·
      3 months ago

      Seems common enough to have a lower mood at night. Idk why really but I’ve always been the same.