cross-posted from: https://piefed.world/c/depression_now/p/933723/does-anybody-else-s-anti-depressants-wear-off-after-taking-a-nap-or-otherwise-sleeping
Duloxetine works great for me until I sleep, then I wake back up into the pit of despair and I feel like I’m supposed to wait until ~24 hours since I last took it in order to take it again. I can’t find any cases of other people reporting this and it’s not something my medical professionals have heard of. It makes it hard if I don’t have energy due to not getting enough sleep the night before so I take a nap, and then when I wake up I still don’t have energy due to lack of willpower. I’ve also found it harder to get out of bed in the morning shortly before taking the medicine.
How bizarre! Usually when I’m having a bad night, sleep helps me because the thoughts quiet down. I’ve been on a low dose of Seroquel. Bad thoughts can get to me at night but I seem to just fall asleep on the med which makes them go away and stay quiet into the next morning!